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17 In addition to mitochondrial dysfunction, oversecretion of corticotropin and anti-diuretic hormone and autonomic dysfunction have also been proposed as causes for CVS

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The two methene bridges and usually the two vinyl groups are then reduced by bacterial flora to form a series of colorless tetrapyrroles called urobilinogens ( 231 )

In the cblC, cblD, cblF, cblG, cblJ, and cblX group of disorders, the synthesis of both adenosylcobalamin and methylcobalamin are affected, leading to combined methylmalonic aciduria and homocystinuria