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It is considered instrumental for regulating mood and mental health thereby improving overall wellbeing and quality of life

Journal of Nuclear Medicine, 53 (1), 98105

Although Pac1r / mice exhibit a complex metabolic phenotype, they display significant glucose intolerance and defective insulin secretion after both oral and iv glucose and impaired insulinotropic responses to PACAP, but not VIP, consistent with the importance of endogenous PACAP for control of insulin secretion (115)