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It delivers a more potent GH pulse than a GHRH analog like Sermorelin but without the significant cortisol and prolactin spikes associated with older GHRPs like GHRP-2 or the formidable Hexarelin

Mimicking the hormones slows digestion and makes patients feel full

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To address the need for strategies to introduce chemical complexity and conformational control into peptide macrocycles, we report here that linear peptides with a reactive N-terminal -keto or -keto amide can be synthesized ribosomally

The potential of GLP-1 agonists extends beyond the physical, too