Of note, dual receptor agonists have significantly advanced incretin-based therapy by concurrently engaging glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptors within a single peptide molecule
A recently FDA-approved higher dose of Wegovy (Wegovy HD) is 7.2 mg, and may result in even more weight loss compared to the 2.4 mg dose
Furthermore, the rising prevalence of obesity has significantly contributed to the growing utilization of GLP-1 analogs in the treatment of obesity, which is significantly driving the GLP-1 analogues market
Even in this last trial, CRP levels were significantly reduced compared to placebo (respectively 42.0% vs 12.8%, estimated treatment ratio 0.67
Ozempic, which was approved by the FDA in 2022, currently retails at P7,560 apiece