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Autoimmune hepatitis (AIH) is a progressive liver condition

NSAIDs presently are the most widely used drugs in medicine and their annual sales in the world are more than 6billion dollars

Researchers studying mucosal integrity, gastric ulcer models, and intestinal permeability have used it to investigate cellular protection mechanisms in laboratory settings

Finally, class 3 compounds, including sitagliptin and teneligliptin, bind to the enzymes active site by anchoring into an accessory binding pocket, referred to as the S 2 extensive side pocket, which is structured by residues Val207, Ser209, Phe357, and Arg358 (87) (Figure 2C)