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Key Takeaways Vitamin B12 is essential for healthy red blood cells, nerve function, and DNA synthesis
While GLP-1 weight loss medication can be incredibly effective, there are important GLP-1 contraindications to consider: Medical Exclusions Absolute contraindications include: Personal or family history of medullary thyroid carcinoma (a type of thyroid cancer) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Severe gastroparesis (delayed stomach emptying) History of pancreatitis (though this is sometimes relative depending on the cause) Situations Requiring Caution Your healthcare provider will carefully evaluate if you have: Kidney disease or reduced kidney function Gallbladder disease or history of gallstones History of depression or eating disorders Pregnancy or breastfeeding (these medications are not recommended during pregnancy) Diabetic retinopathy (may worsen initially with rapid blood sugar improvements) Potential Side Effects to Consider Common side effects that might affect GLP-1 candidacy include: Nausea and vomiting (especially when starting) Diarrhea or constipation Decreased appetite (which is therapeutic but can be concerning if extreme) Fatigue during the adjustment period Most people find these effects manageable, and they often improve over time, but it's important to discuss your tolerance for potential side effects with your provider
Introduction Methamphetamine (MA), a central nervous system (CNS) stimulant, is the third most used recreational drug world-wide ( The notion that MA might damage the human brain is derived primarily from preclinical animal data showing that high doses of MA, or its related stimulant amphetamine, cause loss of brain dopamine neuronal markers ( Although the precise mechanism(s) by which high doses of MA cause brain damage in preclinical studies remain uncertain, excessive oxidative stress is a likely candidate
Regular monitoring is essential throughout treatment
