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It involved three primary steps: (1) Liposome freezing with a cryoprotectant, (2) Primary drying and sublimation, and (3) Secondary drying to remove the remnant moisture [162]

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The lyophilized powder is dissolved in a compatible solvent such as bacteriostatic water

The appropriate choice of the chemical form of vitamin B 12 , the dose, and treatment time will depend on individual factors such as the type of vitamin B 12 deficiency, age, preexisting diseases, type of methylation gene, and medication used

Austin (TX): Schultz Publishing LLC, 2013.48