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The characteristics of ALT responders and non-responders before and after glutathione treatment are shown in Table 3

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These data are in line with our histological findings showing that the disorganization and reduced cell number were primarily observed in the central, (pre-)hypertrophic region of the growth plate, and with our in vitro data revealing that G6PDH deficiency increases oxidative stress and cell death primarily in hypoxic differentiating chondrocytes