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Keywords: Alpha-lipoic acid (ALA), Acute kidney injury (AKI), Kidney transplantation, Diabetic nephropathy (DN), Hypertensive nephropathy, End-stage renal disease (ESRD), Autosomal dominant polycystic kidney disease (ADPKD) Graphical abstract Highlights Alpha-Lipoic acid attenuates acute kidney injury

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Thus, worldwide drug development efforts need re-evaluation and new strategies given that current efforts have been unsuccessful

Genetic-epigenetic dysregulation of thymic TSH receptor gene expression triggers thyroid autoimmunity

TGF-beta activation: GHK-Cu activates latent TGF-beta1, a key fibrogenic signal, in fibroblast models