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Functionally, T cells exhibit enhanced proliferative capacity and reduced exhaustion, while tumor-associated macrophages polarize towards the M1 phenotype [186]
Pharmacokinetic parameters for plasma TMAO, L-carnitine, and TMA Pharmacokinetic parameters for plasma TMAO, L-carnitine, and TMA are presented in Table 3
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Resmetirom is not recommended for patients with cirrhosis, in whom it has not been tested