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The most commonly reported adverse reactions in clinical trials were gastrointestinal: nausea (up to 18 to 24% of users), diarrhea (up to 17%), vomiting, constipation, decreased appetite, dyspepsia, and abdominal pain

Neuroprotection: GLP-1s cross the blood-brain barrier and act on microglia, supporting brain and mood health

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The differences are in their engineering, their regulatory history, and what CJC-1295 brings to the table when paired with Ipamorelin

A publication in the New England Journal of Medicine in 2021 demonstrated that Vafseos safety was not significantly worse than darbepoetin alfa regarding the change in mean hemoglobin levels and that it had a similar safety profile as darbepoetin alfa