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Description

Taken as capsules or powder, stable in gastric juice (survives digestion), best theoretically for gut-brain axis effects

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Dehydration from gastrointestinal symptoms can worsen cold sensitivity, as adequate hydration is essential for proper circulation and temperature regulation

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Contrary to expectations 86 , CV event rate (including stroke) in SELECT was in line with that described in GLP-1RA CVOT conducted in patients with diabetes 84,85

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There were four deaths which occurred during the study

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