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4-6wks Typical cycle duration with proper medical monitoring and planned rest periods 1x/day Once-daily subcutaneous injection due to extended half-life Questions IGF-1 LR3 features a 13-amino acid N-terminal extension that extends its half-life from minutes to 20-30 hours and reduces binding to IGF binding proteins

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Aspirin, diclofenac, ibuprofen, paracetamol and celecoxib were given in dose regimens shown to induce gastric and small intestine ulcers, hepatotoxicity and encephalopathy (8-14), and their effects were timely investigated