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A study examining b.End.3 cells exposed to high glucose levels in vitro demonstrated a dose-dependent increase in permeability, with increased HIF-1 and decreased expression of the TJ proteins, ZO-1 and occludin (Yan et al., 2012)

ApoE2 occurs in roughly 510% of people and is generally associated with a lower risk of coronary artery diseasealthough it may increase the risk of atherosclerosis in certain cases

Garlic, onions, leeks and cruciferous vegetables like broccoli, cauliflower, cabbage, Brussels sprouts and other cabbagey vegetables contain high amounts of sulphur, which helps support glutathione production

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