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Clin Ther 29(1):139153 Buse JB, Rosenstock J, Sesti G, Schmidt WE, Montanya E, Brett JH et al (2009) Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)

Drinking enough fluids and replacing electrolytes can help reduce this risk

Here's how our clinical team thinks about it, and what we actually recommend

By mimicking a naturally occurring hormone, these treatments work to regulate your appetite, slow gastric emptying, and drastically reduce chronic hunger and cravings

So while the direction of the findings is encouraging, particularly for blood sugar, it is fair to say the berberine evidence is not as settled, and long-term data in particular is limited