Tamoxifen inhibits topoisomerases, depletes mitochondrial DNA, and triggers steatosis in mouse liver
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Clinical evidence further links GDM to pulmonary sequelae in offspring: maternal hyperglycemia impairs fetal lung development (He et al., 2023) and is associated with reduced pulmonary function in progeny (Yang et al., 2024)
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Oxidative stress determination is limited in daily clinical practice, primarily due to the difficulty in measuring the different aspects of oxidative stress, which entails several tests: oxidized glutathione, reduced glutathione, glutathione peroxidase, and glutathione reductase (GRd)
