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While research is still ongoing to discover whether this level of muscle loss might have negative consequences for future health, this change in body composition is a potential cause for concern given the importance of muscle mass in maintaining bone density, preserving physical function, immune support and overall metabolic health

"Most side effects of GLP-1 and GLP-1/GIP RAs involve gastrointestinal symptoms, are mild-to-moderate, and improve with time." - Maria D

26,27,2932 Only one study was dedicated to patients with HFpEF and T2D

A combination of interrelated effectors such as glutamate excitotoxicity, mitochondria dysfunction, glial cell pathology, impaired axonal transport, protein aggregations, and neurotrophic factor deficits leads to progressive motor neuron degeneration and eventual death

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