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doi: 10.3389/fcell.2022.821014 39 KapoorMMartel-PelletierJLajeunesseDPelletierJPFahmiH

Improved detoxification Glutathione is a key player in liver detoxification, binding to toxins and facilitating their removal from the body

They inhibit Nrf2 translocation into the nucleus and enhance NFB activation promoting inflammation and oxidative damage (Laforge et al., 2020)

Lmx1b is crucial for the development and differentiation of midbrain dopaminergic neurons, and it is also essential for the differentiation and survival of central serotonin neurons during embryonic development [3, 4, 629, 630]