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The proteins were subjected to the Structure Preparation procedure followed by addition of hydrogen atoms using the Protonate 3D application 71 with all the default settings in MOE

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doi: 10.1080/01902148.2023.2211663 101 Prez-MatuteP.Prez-MartnezL.BlancoJ

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Statements Author contributions All authors made a significant contribution to the work reported, whether that is in the conception, study design, execution, acquisition of data, analysis, and interpretation, or in all these areas, that is, revising or critically reviewing the article