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In recent years, basic and clinical studies have shown that GLP-1 is closely related to lipid metabolism, and it can participate in lipid metabolism by inhibiting fat synthesis, promoting fat differentiation, enhancing cholesterol metabolism, and promoting adipose browning

The main point is structural: when more FDA-approved supply is available, the economic incentive to seek alternatives drops

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Acknowledgements The authors would like to thank Xiaotong Zhangs lab at Zhejiang University for the technical support in data acquisition