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The secretion factor of mesenchymal stem cell-conditioned medium (MSC-CM) decreases the cell surface expression of the GluA1 subunit of AMPAR in cortical neurons

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Evidence in one sentence: Both delivery systems are biologically plausible and supported by limited human biomarker or pharmacokinetic data, but neither has been proven superior for meaningful clinical outcomes

Endpoints and populations differ across trials, and individual outcomes vary

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