SURMOUNT trials: tirzepatide The SURMOUNT trials evaluated tirzepatide for weight management
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International Journal of Preventive Medicine, 3(3), 160-166
In terms of oxidative stress, levels of malondialdehyde (MDA), 8-iso-prostaglandin F2, and 8-hydroxy-2deoxyguanosine (8-OHdG) were significantly reduced, implying that GLP-1RAs reduce lipid peroxidation and oxidative DNA damage
Significant improvements were reported in sperm concentration, total and progressive motility, viability, and DNA fragmentation index before and after cryopreservation