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Clinical data indicate that when patients stop taking the medication, the biological suppression of appetite and the regulation of satiety signals are removed

Table 1 summarizes the results of three representative studies comparing different GLP-1 analogs [17,19,76]

Ascorbic acid (vitamin C) can reduce the Cu2+ ion through Fenton-like chemistry, destabilizing the complex

It also enhances the activity of detoxification enzymes, such as glutathione S-transferases (GSTs), which conjugate toxins to Glutathione, facilitating their elimination (Lu, 2013)

These metabolic shifts can persist for weeks after prednisone is discontinued, meaning blood sugar management challenges may outlast the actual corticosteroid treatment period