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The diuretic and natriuretic effects of GLP-1 are mediated through downregulation of sodiumhydrogen exchanger 3 (NHE3) activity in the renal proximal tubule that consequently affects renal hemodynamics [112]

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FOXO4-DRI is a synthetic peptide designed to disrupt the interaction between the FOXO4 transcription factor and p53, a pathway of interest in cellular senescence research