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It works through a completely different mechanism, stimulating norepinephrine release to suppress appetite

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Self-controlled case analysis of semaglutide exposure showed an increased risk of NAION (meta-analysis incidence rate ratio: 1.32)

[8] Hematologic side effects are of particular concern

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity

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