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[2] and recent studies from the University of New Orleans [75,76])

pylori ) is a Gram-negative, microaerophilic, spiral-shaped bacterium that colonizes the gastric mucosa and damages gastric epithelial cells (GECs)

GRase was another key node in cluster 4, which played a role of bridge between clusters

Ethics declarations Ethics approval and consent to participate The study protocol was approved by the Institutional Review Board (IRB) of the Third Clinical Institute affiliated of Wenzhou Medical University, Wenzhou Peoples Hospital (No: 2021 161)