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Dehydration represents a clinically significant risk for patients taking GLP-1 medications, particularly during the initial weeks of therapy or following dose increases when gastrointestinal side effects are most pronounced

Oxidative stress can damage reproductive cells and decrease fertility potential

In the TOGETHER-PsA trial, patients receiving both Zepbound (tirzepatide) and Taltz (ixekizumab) showed a 64% relative improvement in arthritis disease activity compared to those on Taltz alone

And Glutathione adds its own direct skin benefits beyond recycling Vitamin C

Stay at current dose until eating improves enough to meet minimums