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In contrast, in heart failure with preserved ejection fraction (HFpEF), elevated BP is a major driver of disease progression, and targeted pharmacological therapies remain limited

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Cancer suppression: Experiments have found that MOTS-c can suppress certain types of cancer cell growth by acting through several signalling pathways [18]

In this paper, we consider as outcomes of interest the [GSH]/[GSSG] ratio and the model outputs for the concentration of NADPH, ROS and G6P at time points for which calibration and validation data measurements are available (PN12, PN13, PN15, PN17, PN28)

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