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Records were excluded during screening if they were press releases, news reports, not relevant drug/indication/population, preclinical study, reviews, case reports, not a randomized trial, or not in humans

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The observed decrease in MCP-1 staining intensity suggests that intranasal administration of GHK-Cu in transgenic 5xFAD mice had a reducing effect on the AD-induced inflammatory phenotype and could serve as a reliable prototype to study drugs that slow or stop progression of AD [40]

Semaglutide added to basal insulin in type 2 diabetes (sustain 5): a randomized, controlled trial