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Most of the side effects I saw in practice were related to digestion, including nausea, vomiting, diarrhea, and constipation, along with low energy levels and brain fog (primarily driven by inadequate dietary intake)

Those exploring the combination of semaglutide with B12 are already thinking along the right lines about nutritional support during therapy

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The provider needs to clarify what medical condition(s) or purpose the GLP-1 drug is intended to treat, why it is medically necessary and others arent appropriate, any prior failed treatments, and include additional documentation like clinical notes, says Michaela Robbins, a doctor of nursing practice (DNP) at East x West Med in New York City