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For two of the younger age groups, there were small, but significant decreases in the rate of first-time amphetamine/dextroamphetamine prescriptions across the study period (15-17-year-olds: -0.03, p = 0.005 and 18-29-year-olds: -0.02, p = 0.04)

The ESSENCE (Effect of Semaglutide in Subjects With Noncirrhotic Nonalcoholic Steatohepatitis) trial, 15 a phase 3 study, enrolled 800 patients with biopsy-proven MASH and stage 2 or 3 fibrosis

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