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This comprehensive database systematically collects and analyzes spontaneous reports of adverse drug events and medication errors, enabling the identification and evaluation of potential drug safety signals

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It can be concluded that the dopaminergic deficit is efficiently compensated for a long period of time, at least 10 years or longer, during the normal or near-normal motor activity (silent/prodromal motor period) before clinical symptoms are sufficient for diagnosis (manifested period) [41]

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