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Table 5 Selection of GH signaling pathway stimulators

A treatment-related increase in benign thyroid C-cell adenomas was seen in males in 0.25 and 0.75 mg/kg/day liraglutide groups with incidences of 12%, 16%, 42%, and 46% and in all female liraglutide-treated groups with incidences of 10%, 27%, 33%, and 56% in 0 (control), 0.075, 0.25, and 0.75 mg/kg/day groups, respectively

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Experimental data at times indicates that GHK-Cu exposure correlates with elevated SOD activity and increased levels of antioxidant enzymes, possibly reflecting an indirect enzyme-rescue mechanism rather than direct radical scavenging