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This is particularly common in people who have never used any GLP-1 medication before, those with a history of gastroparesis or other GI conditions, and those who are simultaneously taking other medications that affect gastric motility

Similar to histone lactylation, nonhistone lactylations correlation with various cancer-related diseases has been established, encompassing colon cancer, hepatocellular carcinoma, lung cancer, gastric cancer, prostate cancer, colorectal cancer, and glioblastoma [21, 55, 70, 71, 73,74,75]

But that doesn't mean it's risk-free

Dietary counselingincluding small, frequent meals, adequate hydration, avoidance of high-fat foods, and remaining upright after mealscan further improve tolerability and reduce early discontinuation

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