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In reaction to AD, astrocytes experience a shift in profile, one that is reactive and pro-inflammatory while losing homeostatic roles thus disrupting BBB integrity, ion and neurotransmitter buffering, and energy metabolism (Liddelow et al., 2017

Under post-absorptive conditions, liver glucose, serine, and glycine were comparable between WT and KO mice fed a HF-CTRL diet (Fig

This study did not evaluate any behavioral parameters but did see benefits in some serum markers that are noted to be irregular in patients with ASD

A study on pediatric traumatic brain injury in mice found that acute LM22A-4 treatment preserved myelin integrity and conferred significant neuroprotection

Degeneration of retina-brain components and connections in glaucoma: Disease causation and treatment options for eyesight preservation