GR activity (U/L) = (dOD s / t) x (440 / (OD-CAL - OD-buffer)) x n, where OD-CAL and OD-buffer are the OD 412nm values of the Calibrator and Assay Buffer, t is the reaction time (20 min recommended) and n is the dilution factor
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A neck mass may be present, indicating regional metastasis
How did it become a skin treatment
Secondly, glutaminyl cyclase developer is added to remove pGlu residue and generate the green fluorophore