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Dec 1988;37(12):1595-1607

The injection process for Tirzepatide may result in some discomfort or irritation at the injection site, but such discomfort is usually minimal and short-lived, making it a tolerable aspect of treatment for residents in Tempe, AZ, seeking effective management for diabetes and weight loss

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Mean weight loss of 20.9% at 72 weeks on 15 mg tirzepatide remains the largest mean weight reduction recorded in any Phase III randomized controlled trial of a pharmacological agent, as of mid-2025

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