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Injectable delivery produces measurable plasma levels and allows the peptide to reach tissues that topical application cannot including deeper wound beds, joint spaces in preclinical models, and scalp follicles below the penetration limit of topical creams

Clinical use suggests limited potential for pharmacokinetic interactions, though pharmacodynamic interactions remain possible given BPC-157's effects on vascular tone, growth factor signaling, and inflammatory pathways

Mapping water exchange across the blood-brain barrier using three-dimensional diffusion-prepared arterial spin labeled perfusion MRI

If a lumbar puncture is performed: Consider obtaining an autoimmune encephalitis panel and oligoclonal bands

Bulletin of Experimental Biology and Medicine, 164 , 140-143