doi: 10.1038/nature08186 12 PurcellSMWrayNRStoneJLVisscherPMODonovanMCSullivanPFet al
Materials and methods Reagents and materials Oxidized glutathione (GSH) 2 , homocystine (Hcy) 2 , cystine (Cys) 2 , TCEP, benzyl bromide, 2-chloropyridine, L-lysine, N-acetylcysteine (NAC), 2-mercaptoethanesulfonic acid (MESNA), N-(2-mercaptopropionyl)-glycine (MPG), [2 S]-1-[3-mercapto-2-methylpropionyl]-L-proline (Captopril), and lipoic acid (LA), and ethylenediaminetetraacetic acid (EDTA) were received from the Sigma Aldrich Company (St
GSH deficiency can interfere with the bodys ability to detoxify the cellular environment, fold proteins, regenerate antioxidants, maintain healthy immune responses, and even modulate apoptosis eventsthis promotes suboptimal cellular function and leads to illness [70, 72]
Therefore, this fact provides the foundation for the recommendation that athletes consume a varied diet that is rich in fruits and vegetables (Powers et al., 2004)
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