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Under-transmission of the variation encoding six alanine residues (ALA6) was observed in the families with autistic disorder, suggesting that this allele may be protective

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This is not merely a speculative problem, because both a severely atypical melanocytoma and a melanocytoma-like classical melanoma will likely spread to the regional nodes, but only the latter will be candidates to sentinel node biopsy and, possibly, to an adjuvant therapy with BRAF -inhibitors or with immune checkpoint inhibitors (79, 80)

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