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vila-GlvezMAGimnez-BastidaJAGonzlez-SarrasAEspnJC

doi: 10.1016/j.bbrc.2010.11.054

Amino acids V12 (putative oxyanion hole), F112 (active site architecture), N108 (flavonoid binding) and C13 (GSH stabilization) were fully randomized by site saturation mutagenesis (NNK codons), and the created Pt GSTF8 variants were tested for conversion of flavan-3,3,4-triol ( 4 ) to cyanidin ( 8 ), and for their GSH-transferase activity towards CDNB ( 5 ) as a control of catalytic competence

This is an educational reference, not a self-dosing instruction sheet

SRC Cellular SRC (c-SRC), the product of the SRC gene, is involved in tumorigenesis, invasion, and the metastatic phenotype (Alper and Bowden, 2005)