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There was no statistically significant change in glomerular filtration rate and serum creatine levels in these individuals [36]

The safety profile of 5-amino-1MQ in preclinical studies demonstrates favorable tolerability profiles across multiple research models, providing researchers with a substantial safety margin for experimental applications

Compared with individuals in the metformin and second- or third-line glucose-lowering medications groups, major CVEs were significantly lower in individuals with NAFLD and type 2 diabetes who received GLP-1RAs but not different from those who received SGLT2 inhibitors

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