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On the basis of these findings, the overall efficacy and safety of tirzepatide has been investigated in the SURPASS clinical trial programme in comparison with placebo and other glucose-lowering medications including GLP-1 RAs and basal insulin [11]
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Side effects are most pronounced during dose escalation and tend to improve at each dose level as the body adapts before the next increase
In fact, some studies suggest that coffee consumption may even support certain antioxidant pathways in the liver
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