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Most disulfide-linked drugs are initially freed intact through proteolytic cleavage of the antibody and subsequently released as active metabolites via disulfide exchange or reduction by agents such as glutathione

Discussion This is the first study to simultaneously quantify both cerebral GSH and GABA+ levels in vivo in a large sample of autistic children using HERMES edited spectroscopy at 3T

SRU, Society of Radiology in Ultrasound

The changes in GSH levels induced by such stress are instantaneous and drastic processes, while the generation and replenishment of GSH require a lengthy process, due to involving the rate-limiting indicator glutathione synthetase [43]

doi: 10.4103/jrms.jrms_57_21 46 NordioMBascianiS