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5 [see Warnings and Precautions(5.16)] 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in practice

For instance, our sample had fewer comorbidities as well as a lower proportion of more severely obese individuals

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Angiotensin II stimulates NHE3 activity by exocytic insertion of the transporter: role of PI 3-kinase

While this might not always translate to a clinically significant interaction, it is a factor that your healthcare provider will consider