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This finding highlights not only the key role that mitochondrial metabolism has in modulating response and resistance to TS inhibitors, but the wider opportunity afforded to enhance TS inhibitor-mediated anti-cancer effects by targeting mitochondrial metabolism using metformin or other compounds with similar mitochondrial impact

Published June 23, 2023

I.McBeanG.CindricM.EgeaJ.LpezM

Many people suffer from B12 vitamin deficiency, especially with the growing popularity of veganism, vegetarianism, and other specialty diets and lifestyles

ELISA The ELISA MAX Standard Set Mouse IL-5 (BioLegend) was utilized according to the manufacturers instructions, except that serum samples were incubated overnight at 4 C to enhance the detectability of the generally low serum IL-5 concentrations