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However, these medications profoundly shift metabolic biomarkers within weeks, including fasting glucose, HbA1c, insulin levels, and lipid profiles, which should be monitored regularly to assess efficacy and safety

Semaglutide GLP-1 works by mimicking the natural hormone GLP-1, which helps reduce appetite, increase feelings of fullness, and slow digestion, leading to reduced calorie intake and healthier eating habits

Notably, the NLY01 trial, which enrolled dopaminergic-nave patients, was negative

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