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It is important to notice that The Broad Institute gene profiling was performed with GHK, not GHK-Cu

CJC-1295 (No DAC) is known for producing sustained, dose-dependent increases in growth hormone (GH) and insulin-like growth factor 1 (IGF-1) levels

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And inflamed visceral fat tissue produces its own inflammatory signals, creating a feedback loop where weight gain drives more inflammation, which drives more weight gain