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The mirror image versions of chiral molecules have nearly identical physical properties, making it very difficult to tell them apart or separate them
Kiebik A, Szlasa W, Michel O, et al
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Early warning signs of hypoglycemia may be less obvious in patients with hypoglycemia unawareness which can be due to a long history of diabetes (where deficiencies in the release or response to counter regulatory hormones exist), with autonomic neuropathy, intensified diabetes control, or taking beta-blockers, guanethidine, or reserpine