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For instance, Cohen et al

Our Glutathione Index Test is analysed using liquid chromatographymass spectrometry (LC-MS/MS)the same gold-standard technology used in clinical research and hospitals

Moreover, the OBS was determined under the assumption that the properties of all components exerted a linear effect on oxidative stress, but this did not take into account the threshold effects of anti-oxidants that could exhibit toxic pro-oxidant activity at higher doses or under particular conditions (52)

Thus, current evidence suggests that intralesional verapamil might be beneficial to a subset of patients, especially those in acute phase with minimal calcification